invites to a seminar by
Prof. Wladek Minor
University of Virginia, Charlottesville, USA
The Impact of Reproducibility on Structure Based Drug Discovery
15th of October 2018 at 2 p.m.
Venue: Centre of New Technologies, Banacha 2C,
Lecture Hall 0142 (Ground floor)
Host: Dr. hab. Joanna Sułkowska
Abstract:The drug discovery process depends on the veracity of every decision point on the path from initial experiments to FDA approval, and erroneous data collected along the path can waste valuable time and resources. The presentation will discuss the sources of uncertainty that affect the drug discovery process, focusing on factors that impact structure based drug design the most. The selection of structures used as the basis of computations or data mining will be discussed in detail. All aspects of procedures essential for structural validation and best practices for data management of all experimental steps will be also discussed.